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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'def5d90dbda89cde19bd54078fbe39b053aedbd7ae47353db4ca7ac227db420a' 
  AND token = 'wJ8ZskOIJ3U35/VluH9dkQAGs/UEQnttucN0sKM+ZF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}