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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4f9bfc01df3cd67213048a6d06ee6f5aaf22fd4e4f6d592ccb1e20222e49900' 
  AND token = '0yGjJoCWhD73NQ3xBqLCU4tf8dUnR6+dqS3KmIc9WY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}