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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c8acfca7c0b553b58ccbe989f4b2435c92e5996b32d8af2b61d1e06b3444b71' 
  AND token = 'cxIii0rLkostC+99gez1xfMxqDrMoPXFA88uDKVpA9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}