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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cad9c8ae43e88fa26d84974027163daf23307c4065d66bbaa08dc4b964edd7b' 
  AND token = 'igXFvdmkgg5K0ROgExV/nPRl8WW0qqzu265cBgte6gE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}