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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05c9f309e1bdca0058890a376378d9b6f37e55bb17343cbb7fc1326efd03cd49' 
  AND token = 'w16y0IaYDtofo35hPdylDKo1Yp7R2INcuSAdZGG9qgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}