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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f795babffabf2c73cdff7ac5e322c40f6a8e44abcd7ebb765968fc4dd0d5b00' 
  AND token = 'XGSZfChajBtjkTCzC+IkT4F+QTqVsis1Zrd0ID8X100=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}