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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f26175f768e107cd881f27a28650dbb359d49d1f7e2245af705b6a008be734b8' 
  AND token = 'Wb24S8+o5rDmephllsWxSm5U5xDoI7pbZQrGL1XZPNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}