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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b99635a9fa9c95b5076090bf36470adff6990aea7db247b1c026f704319945cd' 
  AND token = 'MbEi6J4gW+RQoDcXC9nnmsDHdG9ESyK8nh3WV9IEoUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}