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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '888491bd3da0e82bdedfb01c43dc9122722610de8f2bf48f8cc233e3e8f6ded0' 
  AND token = 'u0RtCw6S1H1zVR8bP4ritj4bgGpDTkrCG772nDS9Bdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}