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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6824c5d343761d98d4b1c72d10d615d98a304622a3a532081b4be7fbf896672' 
  AND token = '1Tp6inNuFxj/IpGhPES/lvUSxArdo/FQpAzNjTG1p9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}