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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48f60189991ba8ee7f2a0b6d28599e32b9bd4520c682c7dd6ad2f4f89841236a' 
  AND token = 'yOqIsk3CnaZ3X42FTbLvHYL1GOkxUTEoDQmPOSNwHLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}