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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe46cd4bc06c487e8c7602ba11c2a388f1b266ea6a6723f91ac2bcb017141743' 
  AND token = 'f0Cl/p87MhB0YaIHX6SFYQTVaGhr80I1xFWtSu0uv4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}