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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1ec0a389591a9e2f0c30c880749229308d35cbec8296d49bf20bd129b2e9eb8' 
  AND token = 'oEP59MpA67CviSq+cDiOP/wp4nhbtZrnwySXyJbgEOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}