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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84c8eb50fdd1d4feb7fe98490b472c84dc747b4bd2d2edbfc4bbd3b041e16201' 
  AND token = 'px0aQ7KjGwJO1KFw1tXB8dUHq7pNwNMI+5hOc5YvLxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}