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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16e7e70ba516f8a0cba6393c8fcafbbaa5b91c7719364e303e6d7124f5f369ed' 
  AND token = 'jDauAFTGd6FAqQAyEDh5bK9ulK1jlSWhzMB+1sMdDMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}