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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7fd53ef0a44deded83608612caa0ddf427e51bc0857056d6f5dedbcf965b1b8' 
  AND token = 'nzutVY/++KTL6F3nq8oiwQSVH6rABwi57fSRRYxWNx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}