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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0e6c5532823e2767c287da05ed0e9200e9b10409589b60fd6abf5591675c6d2' 
  AND token = 'vVlQJpPzq7ObcVQTlJk9Zy6kOo6KL9ck5T6kR6DCG74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}