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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e879699fdd0cc40f0aa6be2dcef59dfb270f6ec466901bd8a0772dac9de7c3b' 
  AND token = 'iJfSz/JqPh/7Z0BerIXlyIsryUpSkpFeE5PMSUXAUoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}