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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '708b84ae24c16a56070c99bd54ff8da7cd4b56709cba0ccd715c36217a21819f' 
  AND token = 'opnCkQkfVJOeI1+IEAP3dl5QNdH2abRgrSrgdw+bfcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}