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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caf12edc8ff6e536863a0cec65b2407cf04acabbc3d6c11e06c53fc6acc51fdc' 
  AND token = 'BHLfGRLMLXdsx7y8NMjk2hU3Cj59f/Xt60L2Uigr3bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}