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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0d1fdc47d4d575a5858ee1574b5c02112ebd83e96429a318c8e18a127dfb7e0' 
  AND token = '6S36msMR3BFzqwSK3SzOc6NPWb7iuWFUgwCc2lcddNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}