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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff78d9a8591d9df5aeca22966d6b9de3562b49b09627fb432bc36b7b82065e5d' 
  AND token = 'uxh3u3/67tdIsdFtuNRPhPhp075szYC3yL8aJRByknA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}