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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c016e99f9ba6ab7c72e214a0ffa7e35c0624b4efcb769a76847dfe43c7c0289' 
  AND token = 'P9R3A4ZUOJJUnvrBmP3uC3rMxtGH4MlWuKAl/z0hcl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}