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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '682dd315f34a6ad64f291754f588748a321dd82f814d7c3391dfae3613ac3975' 
  AND token = 'QO+7ViPIrjMdE9WsWAgDn96GeSn7xnJMY8udZ5DAsQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}