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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46edfdf7e6ab24317b8c51462cfecff24186cc46a43c61351f9f36ba340136fa' 
  AND token = 'QhQPn/XxV4IyPsqx/8lUzQMjDAbVAcZb706QhguzUrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}