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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff4dde3413ca2d0a3caf63f410541aef1617362fbe61c9aa9c2454afa34ed8a5' 
  AND token = 'AEVlMNQ0b3RgEViZARpEZv5eh1fwfYWWV/6e3RKy1cI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}