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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7331833b79ca39e9034ede0be836c1e43de62041de52db468faf15c7da15040' 
  AND token = 'PXYc4Q4FOFOqUx0ZmgVJgsSTr+YTHdcTF77AtNFVgxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}