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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd901ed70010b6be3936d5ac09b7077dd5227681599c1f7dc1b362676d65b8b27' 
  AND token = 'C0Xn8EeoqQNWEkJ9zy/wA0lrmlz9Pb1zcyM6b7KyIF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}