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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8701281564ec7263393da51d91039b5b5bf62138ffce6a2574efe0ffaf1f6263' 
  AND token = '+Q5T3C0MY4z1Va2kLCkM2TtgdcLAJEApMYPzYktHLpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}