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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '222990fee823e6b74a900e84da647b7c628d825a14b497cabd8b4e4fe0dffe05' 
  AND token = 'lWraGwBNL4mxZTsYVHT55BbEZ1Vx0PBR550dRXWZ2wQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}