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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6ad9c614e20de35d7a07a144610ecf15d5ff383a5d611eb56bf3374fbe6e31c' 
  AND token = 'DPrwmu6X3c4qjXaB9YMji/eWiV0axYpc34z9dGkKW5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}