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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af22b1b3e1a30e10d44bc0cc38a73e2a134fed3ff84c03ae2eb7c0a885f476a0' 
  AND token = '2C2p+VJAGx2ubRzlGyIMjit75XtVltys7IbQOWHTO1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}