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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67886e95f0e008d52af74d2a5b8c589199d2c527f0f555ee6d2cc4efc1b3b0f6' 
  AND token = 'EFqxA8BrZm+oyZeT4CWWu/y9tupZSDPoDvygHB5g+Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}