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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f8576c5fda04ff5d63d7b528264fc5e36937b3b7181ed3e9ddf9affabb10316' 
  AND token = 'HOEWdmYKg6fWiJ3PFrS/HNvGaM5YEwBkSdE2WTyZ7CU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}