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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3480b08ba9234fa52c2a98098ad3dc4063685ed9934bcd905ab6d40107b9c0ac' 
  AND token = 'vDFR4Ru52C9J4eyt6ySgLcEhM+NdtJ5qFG0oXdmtYVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}