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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8f90e838b5f24b9030bdb4195854980719b52a60a98675a305d0f169273d885' 
  AND token = '1HCY67EWI4a+dsktgiDYXZejvf/ifLb4wB6D5fl/d/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}