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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a463eeaf61a0a82c838519fb74e51c7fe467a067ef92b45a45f3edaa23a2972d' 
  AND token = 'Eaxxh4P5g5r/p1TwdagTQdy6zYSaQen4ttlBqoxQcN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}