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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f9de27cd492a0f3feb4cc068caa1f0514cc36dd5bb2136ed2f9a1127a81c997' 
  AND token = '2YjdtdSqkRVyCc7EyD91qHcfDZs5A4DQepwZ37e9hZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}