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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e3d7ee013f1d2fd5db021e4442b026844e382a0734735c4a50fbd95755e4be1' 
  AND token = 'sbFC5ZOhyIN4F0vYBSbt/e7qUZ98WK1Fy+1BYiVBJt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}