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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f342c8a413f1ca252f72147210f364dbd7784e962b0f70fd7e83d646aafbc3c3' 
  AND token = 'MDlclRY3RgMYSD47fDhfiRkf15Yho1HbjYDh3frmdlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}