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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f0498597ef92f65e4b11b7b4637e5b1770e1028644cb92ff8603870ebc76652' 
  AND token = 'daa9T9NEFmfNwGRJp+8MQyacsSncqL3jS/T8NuXeiGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}