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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '436c7647bdfa1c0734710dd1cf03cd51ad6e362e8df4640a96c9648f7e9401c1' 
  AND token = 'elAJFW/otr0b3LxMFxe1GtT/CPIYM/MZg22MO2dN/3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}