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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '060aedf2df7b8b3343f807085957097ee704aebebcf7088c5c30270e25c192e9' 
  AND token = 'y7icnINXv//xGXa299W4372/0YM2dmXH8deGVyAz69I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}