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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd887902c3e61828960339540287c7e68e66f67b2b4f9505c9b03e7837984c326' 
  AND token = 'dRuoAdD3lT6Hg8G4gop9x3tZcJt5oemHGkRAE8QrlSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}