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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a21c9ec6c60855ebbc02b9519c3430453dc00da24021240b61c3bafcf3fc287' 
  AND token = '6zAo1If7CC8yte+Zn6qVFZQxkASSZzLUg5EnIrSyUZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}