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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c42ccf661fd68e88ed4c24c94c5275c16ca934526c38acb628a9221eac2e696a' 
  AND token = 'NIKlqh10VvN+LmcF5V61EHfwpk3HXDcQMcc0o+Yc2P4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}