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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e8719f61cf1937440ded68a76ce1f0b6500ba7c32f36b0474dc3f4bff24d775' 
  AND token = 'Z6Q2K8ZOyjm3nkWtcGeuRHuq7Qvu6eY4Rq+CHXawC2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}