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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33440c6431e6058953681d803d9551859d3227a4c2511f9980739fe067fca411' 
  AND token = 'ghuCe2T68zwpkMMQwu97DEEVrVMnqHOWE/nGFyzkHnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}