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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ad8bcdc7021defd2b3d49a1f846981be638ce2ef56ccd9d53e93c7924853cc4' 
  AND token = 'jBHoLDkhf9mdE8sSZUCrxHidjdU0eW3iRrv4ZaUsMSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}