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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0644c4be42d25ab14409b2cf562edbb5218341ec8e049b7e04b5c4c6700bf53c' 
  AND token = 'GaRL0W603tvOwXqoiFOBWqdn9ZSUVkpItvfBY016Who=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}